New publication in Organometallics!

In this paper, just reported in Organometallics, we describe the results of a computational investigation that shed light on the catalyst structure–activity and selectivity relationships for our recently developed Rh(I)-xantphos-catalyzed transfer C–H borylation of alkenes (c.f., Chem Catal. 2022, 2, 762-778). The study provides guidelines for the rational development of new catalysts to further enhance the performance of the catalytic system and address the remaining challenges.

https://pubs.acs.org/doi/10.1021/acs.organomet.2c00148

Congrats to all!

Congratulations to Dr. Sebastián Martínez

After an excellent presentation and a thorough scientific discussion with the jury members – Prof. Bill Morandi, Prof. Bas de Bruin, Prof. Philippe Dauban, Dr. Joanna Wencel-Delord, and Prof. Thomas Ebbesen, Sebastián successfully defended his PhD thesis and was granted a doctorate title. Congratulations and good luck for the future! Special thanks to the jury members!

New publication in Chem Catalysis

In this paper, we present a broadly applicable method for the C–H borylation of various alkenes, that is, a valuable transformation in the synthesis of fine chemicals, such as pharmaceuticals and agrochemicals. Importantly, the reaction tolerates a plethora of functional groups and can be used for the late-stage functionalization of complex bioactive molecules, such as derivatives of zearalenol and brompheniramine. The study provides insight into the reaction mechanism and the features controlling the selectivity, thereby setting the stage for the development of other related valuable reactions.

https://www.cell.com/chem-catalysis/fulltext/S2667-1093(22)00103-8

Congrats to all!

New publication in Synthesis!

In this review article in a special issue of Synthesis – “Bürgenstock Special Section 2021 – Future Stars in Organic Chemistry’, we provide an overview of different approaches in the field of C–H borylation reactions mediated by group 9 metal-based catalysts that target the control of the activity and the selectivity of the reaction, with the main focus on recent studies.

https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1711-5889