Regio- and Enantioselective Alkoxycarbonylation of Unactivated Terminal Alkenes under Palladium-Bromide-Monophosphine Catalysis

M. Sigrist,# K. Das,# G. Kurpik,# W. Tian, J. Huang, A. Covas, A. D. Bond, W. Tang, P. Dydio

J. Am. Chem. Soc. 2026148, 26960−26969

Regio- and Enantioselective Alkoxycarbonylation of Unactivated Terminal Alkenes under Palladium-Bromide-Monophosphine Catalysis

M. Sigrist,# K. Das,# G. Kurpik,# W. Tian, J. Huang, A. Covas, A. D. Bond, W. Tang, P. Dydio
J. Am. Chem. Soc. 2026148, 26960−26969

Dehomologative C–C Borylation of Aldehydes and Alcohols via a Rh-Catalyzed Dehydroformylation–Borylation Relay

K. Das, N. Kuznik, P. Dydio
J. Am. Chem. Soc. 2025147, 16735-16741

Dual relay Rh-/Pd-catalysis enables β-C(sp3)–H arylation of α-substituted amines

Photoinduced Cu(II)-Mediated Decarboxylative Thianthrenation of Aryl and Heteroaryl Carboxylic Acids

Z. He, P. Dydio
Angew. Chem. Int. Ed. 202463, e202410616

Multi-Stimuli-Responsive Network of Multicatalytic Reactions using a Single Palladium/Platinum Catalyst

G. Kurpik, A. Walczak, P. Dydio, A. R. Stefankiewicz
Angew. Chem. Int. Ed. 202463, e202404687
featured as a Very Important Paper

A Merger of Relay Catalysis with Dynamic Kinetic Resolution Enables Enantioselective β-C(sp3)-H Arylation of Alcohols

B. Lainer, S. Li, F. Mammadova, P. Dydio
Angew. Chem. Int. Ed. 202463, e202408418
featured as a Hot Paper
highlighted in Synfacts, 2024, 20, 946

Iodide-Assisted Pd Catalysis as an Attractive Alternative to Rh Catalysis for the Industrially Relevant Isoselective Hydroformylation of Simple Aliphatic Alkenes

Y. Zhang, M. Sigrist, S. Martínez, J. Bojanowski, C. Antheaume, J. M. Granda, P. Dydio
Synlett 202334, 1185-1194

Multicatalysis Enables Turning Plastic Waste into Chemical Commodities

S. Martínez, P. Dydio
Trends Chem. 2023, 5, 249-251

Variable Structure Diversification by Multicatalysis: The Case of Alcohols

B. Lainer, K. Das, P. Dydio
Chem. Commun. 202359, 4716-47251

The 55th Bürgenstock Conference under the Banner of Sustainability (Meeting Report)

A. Nowak-Król, P. Dydio
Angew. Chemie Int. Ed. 202261, e202214722

Shapeshifting xantphos

L. Veth, P. Dydio
Nature Chemistry 202214, 1088

Density Functional Theory Studies of the Catalyst Structure–Activity and Selectivity Relationships in Rh(I)-Catalyzed Transfer C–H Borylation of Alkenes

S. Martínez, P. Dydio
Organometallics 2022, 41, 1649–1658

Transfer C–H borylation of alkenes under Rh(I) catalysis: Insight into the synthetic capacity, mechanism, and selectivity control

L. Veth,# H. Grab,# S. Martinez,# C. Antheaume, P. Dydio
Chem Catal. 20222, 762-778
featured on the cover of the issue

Isoselective Hydroformylation of Propylene by Iodide-Assisted Palladium Catalysis

M. Sigrist, Y. Zhang, C. Antheaume, P. Dydio
Angew. Chemie Int. Ed. 2022, 61, e202116406

Teaching natural enzymes new radical tricks (Perspective)

Y. Zhang, P. Dydio
Science 2021374, 1558-1559

Recent Trends in Group 9–Catalyzed C−H Borylation Reactions: Different Strategies to Control Site-, Regio-, and Stereoselectivity (Short-Review in the ‘Bürgenstock Special Issue 2021 – Future Stars in Organic Chemistry)

L. Veth,# H. Grab,# P. Dydio
Synthesis 202254, 3482-3498
featured on the cover of the issue

Challenges and Opportunities in Multicatalysis (Perspective)

S. Martinez,# L. Veth,# B. Lainer, P. Dydio
ACS Catal. 202111, 3891-3915

Enantioselective α-Arylation of Primary Alcohols under Sequential One-Pot Catalysis

B. Lainer, D. Lichosyt, M. Aleksandrova, P. Dydio
J. Org. Chem. 202186, 9253-9262

Multicatalytic Approach to One-pot Stereoselective Synthesis of Secondary Benzylic Alcohols

A. Casnati,# D. Lichosyt,# B. Lainer, L. Veth, P. Dydio
Org. Lett. 2021, 23, 3502-3506

Palladium-Catalyzed Hydroformylation of Alkenes and Alkynes (Mini-review for the GDCh Chemieodzententagung 2020 Dresden)

Y. Zhang, M. Sigrist, P. Dydio
Eur. J. Org. Chem. 2021, 2021, 5985-5997

Binuclear Pd(I)-Pd(I) Catalysis Assisted by Iodide Ligands for Selective Hydroformylation of Alkenes and Alkynes

Y. Zhang, S. Torker, M. Sigrist, N. Bregovic, P. Dydio
J. Am. Chem. Soc. 2020, 142, 18251-18265

Dual-Catalytic Transition Metal Systems for Functionalization of Unreactive Sites of Molecules

D. Lichosyt, Y. Zhang, K. Hurej, P. Dydio
Nature Catal. 20192, 114
featured on the cover of the issue

Effector Responsive Hydroformylation Catalysis

S.-T. Bai, V. Sinha, A. M. Kluwer, P. R. Linnebank, Z. Abiri, P. Dydio, M. Lutz, B. de Bruin, J. N. H. Reek
Chem. Sci. 201910 (31), 7389–7398

The influence of binding site geometry on anion binding selectivity: a case study of macrocyclic receptors built on an azulene skeleton

D. Lichosyt, S. Wasiłek, P. Dydio, J. Jurczak
Chem. Eur. J. 201824, 11683

Enzymatic, Chemoselective C-H Amination Catalyzed by CYP119 Containing an Ir(Me)-PIX Cofactor

P. Dydio,# H. M. Key,# H. Hayashi, D. S. Clark, J. H. Hartwig 
J. Am. Chem. Soc. 2017139, 1750
highlighted in JACS Spotlights 2017, 139, 1705

Beyond Iron: Iridium-Containing P450 Enzymes for Highly Selective Cyclopropanations of Structurally Diverse Alkenes

H. M. Key,# P. Dydio,# Z. Liu, J. Y-E. Rha, A. Nazarenko, V. Seyedkazemi, D. S. Clark, J. H. Hartwig 
ACS Cent. Sci. 20173, 302

An Artificial Metalloenzyme with the Kinetics of Native Enzymes

P. Dydio,# H. M. Key,# A. Nazarenko, J. Y-E. Rha, V. Seyedkazemi, D. S. Clark, J. H. Hartwig
Science 2016354, 102-106
highlighted in Chemical & Engineering News 2016, 94, 8

Abiological Catalysis by Artificial Haem Proteins Containing Noble Metals in Place of Iron

H. M. Key,# P. Dydio,# D. S. Clark, J. H. Hartwig
Nature 2016534, 534-537
highlighted in:
(i) Chemical & Engineering News 2016, 25, 6
(ii) Nature 2016, 537, 156
(iii) Angew. Chem. In. Ed. 2016 (10.1002/anie.201607222)
(iv) Chemistry World RSC, 6/14/2016: Metal ion swap improves artificial enzymes
(v) Nature Podcast on 06/16/2016
(vi) The Daily Californian, 7/04/2016: Berkeley Lab researchers combine synthetic, natural catalysts to create new reactions 

Cofactor-Controlled Chirality of Tropoisomeric Ligand

L. Théveau, R. Bellini, P. Dydio, Z. Szabo, A. van der Werf, R. A. Sander, J. N. H. Reek, C. Moberg
Organometallics, 20161956–1963

Azulene-Based Macrocyclic Receptors for Recognition and Sensing of Phosphate Anions

D. Lichosyt, P. Dydio, J. Jurczak 
Chem. Eur. J. 2016, 22, 17673

Diamidonaphthalenodipyrrole-derived Fluorescent Sensors for Anions

J. Jurczak, P. Dydio, P. Stepniak, T. Zieliński
Sensor Actuat B Chem. 2016, 237, 621–627

A hybrid macrocyclic anion receptor exploiting the pyrrole-2,5-diacetamide unit

J. Jurczak, P. Dydio, P. Stepniak, T. Zieliński
RSC Adv. 20166, 41568-41571

Beyond Classical Reactivity Patterns: Hydroformylation of Vinyl and Allyl Arenes to Valuable b-and g-Aldehyde Intermediates using Supramolecular Catalysis

P. Dydio, R. J. Detz, B. de Bruin, J. N. H. Reek
J. Am. Chem. Soc. 2014136, 8418–8429

Scalable and chromatography-free synthesis of 2-(2-formylalkyl)arenecarboxylic acid derivatives through the supramolecularly controlled hydroformylation of vinylarene-2-carboxylic acids

P. Dydio, J. N. H. Reek
Nat. Protoc. 2014, 9, 1183−1191

Supramolecular control of selectivity in transition metal catalysis through substrate preorganization (Perspective)

P. Dydio, J. N. H. Reek
Chem. Sci. 20145, 2135−2145

Precise Supramolecular Control of Selectivity in the Rh-catalyzed Hydroformylation of Terminal and Internal Alkenes

P. Dydio, R. J. Detz, J. N. H. Reek
J. Am. Chem. Soc. 2013135, 10817-10828

Supramolecular control of selectivity in hydroformylation of vinyl arenes: easy access to valuable b-aldehyde intermediates

P. Dydio, J. N. H. Reek
Angew. Chem., Int. Ed. 201352, 3878-3882
featured as a Very Important Paper
 featured on the back cover of the issue
highlighted in Nat. Chem. 2013, 5, 250

Selective Isomerization-Hydroformylation Sequence: a Strategy to Valuable α-Methyl-Branched Aldehydes from Terminal Olefins

P. Dydio, M. Ploeger, J. N. H. Reek
ACS Catal. 20133, 2939–2942

Dynamic Combinatorial Chemistry in Chemical Catalysis

P. Dydio, P.-A. R. Breuil, J. N. H. Reek 
Isr. J. Chem. 201353, 61-74

7,7’-Diamino-2,2’-diindolylmethane: a Building Block for Highly Efficient and Selective Anion Receptors Studies in Solution and in the Solid State

P. Dydio, D. Lichosyt, T. Zieliński, J. Jurczak
Chem. Eur. J. 201218, 13686-13701

“Cofactor”-Controlled Enantioselective Catalysis

P. Dydio, C. Rubay, T. Gadzikwa, M. Lutz, J. N. H. Reek
J. Am. Chem. Soc. 2011133, 17176-17179
highlighted in Chemical & Engineering News 201189, 13
highlighted in Chemistry World RSC, 10/18/2011: Cofactor control of catalysis enantioselectivity

Remote Supramolecular Control of Catalyst Selectivity in the Hydroformylation of Alkenes

P. Dydio, W. I. Dzik, M. Lutz, B. de Bruin, J. N. H. Reek
Angew. Chem. Int. Ed. 201150, 396-400
featured as a Very Important Paper
 featured on the back cover of the issue
highlighted in ChemCatChem 2011, 3, 619-621
highlighted in Wiley ChemistryViews, 01/24/2011: Control of Selectivity in Hydroformylation

Amide- and Urea-Functionalized Pyrroles and Benzopyrroles as Synthetic, Neutral Anion Receptors (Critical Review)

P. Dydio, D. Lichosyt, J. Jurczak
Chem. Soc. Rev. 201140, 2971-2985

Benzopyrrole derivatives as effective anion receptors in highly competitive solvents

J. Jurczak, M. J. Chmielewski, P. Dydio, D. Lichosyt, F. Ulatowski, T. Zieliński
Pure Appl. Chem. 201183, 1543-1554

7,7′-Diureido-2,2′-diindolylmethanes: Anion Receptors Effective in a Highly Competitive Solvent, Methanol

P. Dydio, T. Zieliński, J. Jurczak
Org. Lett. 201012, 1076-1078

Anion receptors based on 7,7’-diamido-2,2’-diindolylmethane

P. Dydio, T. Zieliński, J. Jurczak
Chem. Commun. 2009, 4560-4562

Bishydrazide Derivatives of Isoindoline as Simple Anion Receptors

P. Dydio, T. Zieliński, J. Jurczak
J. Org. Chem. 200974, 1525-1530

Synthesis, structure and the binding properties of the amide-based anion receptors derived from 1H-indole-7-amine

T. Zieliński, P. Dydio, J. Jurczak
Tetrahedron 200864, 568-574